Hmm, well I don't have much experience in this match up but I do play against Zane whenever I can. He and I were discussing it and it's all about how well Ezio can space ZWEI. If Ezio can stay out of Ein's attack range than Ezio can whiff punish pretty easily. Also Zwei can't summon zwei with 1 and 4[A] at a distance because Ezio can crossbow him out of it.