Ghengis_John
[13] Hero
Blood.
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Blood.
AnitaLife
[10] Knight
wtf my annoying parents are using my netflix account gtfo i wanna play sc4
XxAnEpicGamerxX
[09] Warrior
So 2 Black Guys Walk Into A Convenient Store And Goes To The Counter..... I Think We Know What Happens Next. ;D
NightmareCometh
[08] Mercenary
they purchase their items and give the shop owner their thanks before moving on with their day, am i riiiiiight
OK so I have to write a research paper for my English class and I chose AIDS lol I just figure it there is a lot of research on it, And I am just not in the mood to dig... Also I am fascinated by this virus... Anyways here something I came across that I thought I would share!
U.S. Gamers Crack Puzzle in AIDS Research that Stumped Scientists for Years
In just three weeks, online gamers deciphered the structure of a retrovirus protein that has stumped scientists for over a decade, and a study out Sunday says their breakthrough opens doors for a new AIDS drug design.
The protein, called a protease, plays a critical role in how some viruses, including HIV, multiply. Intensive research has been underway to find AIDS drugs that can deactivate proteases, but scientists were hampered by their inability to crack the enzyme's structure.
Looking for a solution, researchers at the University of Washington turned to Foldit, a program created by the university a few years ago that transforms problems of science into competitive computer games, and challenged players to use their three-dimensional problem-solving skills to build accurate models of the protein.
With days, the gamers generated models good enough for the researchers to refine into an accurate portrayal of the enzyme's structure. What's more, the scientists identified parts of the molecule that are likely targets for drugs to block the enzyme.
"These features provide opportunities for the design of antiretroviral drugs, including anti-HIV drugs," the authors wrote.
Proteins are made up of long chains of amino acids that fold into complex shapes, but their structures are difficult even for computers to predict.
"We wanted to see if human intuition could succeed where automated methods had failed," said Firas Khatib, a lead author of the study, published in the journal Nature Structural & Molecular Biology.
The researchers were hopeful that their finding would open further possibilities of crowd-sourcing and online game-playing in scientific discovery.
"The ingenuity of game players is a formidable force that, if properly directed, can be used to solve a wide range of scientific problems," Khatib said.
Seth Cooper, a co-creator of Foldit, added, "People have spatial reasoning skills, something computers are not yet good at. Games provide a framework for bringing together the strengths of computers and humans. The results in this week's paper show that gaming, science and computation can be combined to make advances that were not possible before."
U.S. Gamers Crack Puzzle in AIDS Research that Stumped Scientists for Years
In just three weeks, online gamers deciphered the structure of a retrovirus protein that has stumped scientists for over a decade, and a study out Sunday says their breakthrough opens doors for a new AIDS drug design.
The protein, called a protease, plays a critical role in how some viruses, including HIV, multiply. Intensive research has been underway to find AIDS drugs that can deactivate proteases, but scientists were hampered by their inability to crack the enzyme's structure.
Looking for a solution, researchers at the University of Washington turned to Foldit, a program created by the university a few years ago that transforms problems of science into competitive computer games, and challenged players to use their three-dimensional problem-solving skills to build accurate models of the protein.
With days, the gamers generated models good enough for the researchers to refine into an accurate portrayal of the enzyme's structure. What's more, the scientists identified parts of the molecule that are likely targets for drugs to block the enzyme.
"These features provide opportunities for the design of antiretroviral drugs, including anti-HIV drugs," the authors wrote.
Proteins are made up of long chains of amino acids that fold into complex shapes, but their structures are difficult even for computers to predict.
"We wanted to see if human intuition could succeed where automated methods had failed," said Firas Khatib, a lead author of the study, published in the journal Nature Structural & Molecular Biology.
The researchers were hopeful that their finding would open further possibilities of crowd-sourcing and online game-playing in scientific discovery.
"The ingenuity of game players is a formidable force that, if properly directed, can be used to solve a wide range of scientific problems," Khatib said.
Seth Cooper, a co-creator of Foldit, added, "People have spatial reasoning skills, something computers are not yet good at. Games provide a framework for bringing together the strengths of computers and humans. The results in this week's paper show that gaming, science and computation can be combined to make advances that were not possible before."
So next time someone tells you playing video games is useless...
Serious yeah, I know trippy right!
Ghengis_John
[13] Hero
So yeah that story's legit. It's pretty much all over the internet at the moment. What I'm fond of pointing out is how science can be advanced by having a little faith in people without a couple of expensive letters attached to their names. Clearly these scientists suck at puzzles and are simply too proud to come right out and say "we're not as smart as some of the people out there.".
PANDA
[13] Hero
seriously, these scientist are so narrow minded. they can't get the big picture.
K0rN_b4LL
[14] Master
DAMMIT! I came in here to post the yahoo article on that HIV thing and you beat me to it. 
These scientists are the brilliant ones!But science is all about experimenting and discovering, you can fault them for not knowing it is a process of discovery!
The more I learn the more fascinating this hall thing is.
I guess the main theory of HIV which is the cause of AIDS is that it was originally a virus called SIV that was in chimpanzees. That virus most likely got mixed up with another apes virus and than mutated and than mutated again when it was introduced to humans (most likely hunters in Africa that eat ape brain soup and shit like that) Than there is also a lot of prostitution and from there things got out of control. But the most interesting thing is the Virus itself which has the ability to Mutate and adopt! Its crazy!
The other thing the is interesting is the fact that some people (European decent) are immune to HIV. It so trippy I am learning much. Seriously this is the best topic for a research paper there is so much info!
The more I learn the more fascinating this hall thing is.
I guess the main theory of HIV which is the cause of AIDS is that it was originally a virus called SIV that was in chimpanzees. That virus most likely got mixed up with another apes virus and than mutated and than mutated again when it was introduced to humans (most likely hunters in Africa that eat ape brain soup and shit like that) Than there is also a lot of prostitution and from there things got out of control. But the most interesting thing is the Virus itself which has the ability to Mutate and adopt! Its crazy!
The other thing the is interesting is the fact that some people (European decent) are immune to HIV. It so trippy I am learning much. Seriously this is the best topic for a research paper there is so much info!
K0rN_b4LL
[14] Master
I read somewhere (I forget where) that a guy with HIV had a bone marrow transplant or something from a guy who was immune and a year or two later the first guy was cured of HIV.
Yeah I read that, it's true!
hever
[12] Conqueror
I don't know what to say, but uhh... yeah.
Mage
I'll make you submit!
Ghengis_John
[13] Hero
My guess would also be that the leap was made through Bush Meat, (probably improperly cooked or handled) but all viruses have the ability to mutate and adapt, that's why we see a new flu every year. Well that and Chinese farming practices could stand some hygienic scrutiny.
yes!! Bush meat that's what I meant, thank you. But the HIV virus ability to mutated and adopt even to medications! It's is more complicated...
Isaiah
[10] Knight
This girl im talkin to was like she dont suck but she not a virgin. SO THIS GO OUT TO ALL THE GIRLSTHOSE WHO SAY YOU DONT SUCK DICK!!!!!
