DINO, one thing I recently discovered that really surprised me and might be quite a sticking point for Voldo is that post 2A+B might be fully reactable. When I played Krayzie even on a crappy online connection he was able to react to the cancel and interrupt before I could get a move in. I also know there are players who can beat CR mixups by crouching and rising vs CR K. Combining those two, when you 2A+B someone they could crouch and then interrupt your cancel if/when they detect it. This completely shuts down all options after 2A+B. To be fair many solid players I played offline weren't able to react to the cancel so it's fairly hard, but it doesn't seem impossible.
I do sometimes use 66B outside combos. Sad as it is 66B is tied for Voldo's fastest mid (facing forward) and it does way more damage than BB, so if someone is cheating on frames it's a pretty good option. Also it is still safe against the vast majority of the cast, although it spaces very poorly (tends to leave you in grab range or very close to it).